CV

Education

Ph.D in Bioengineering (Biomedical Signal and Image Processing track), University of California, Los Angeles, 2021
M.S. in Chemistry (Biophysics track), University of California, Los Angeles, 2017
M.B.B.S. in Clinical Medicine, Shanghai Jiao Tong Univeristy, 2015

Work experience

June 2021 - December 2022: Postdoctoral Researcher
- University of California, San Francisco
- Department of Radiology & Biomedical Imaging
- Advisors: Dr. Janine Lupo, Dr. Peder Larson
July 2017 - March 2021: Graduate Student Researcher
- University of California, Los Angeles
- Department of Bioengineering
- Advisor: Dr. Benjamin Ellingson

Skills

Programming Languages
- MATLAB, Python, C++, LaTeX
Neuroimaging Softwares
- AFNI, FSL, FreeSurfer, SEPIA

Publications

Magnetic Resonance Nano-Theranostics for Glioblastoma Multiforme

J. Yao, C. Hsu, Z. Li, T. Kim, L. Hwang, Y. Lin, Y. Lin, "Magnetic Resonance Nano-Theranostics for Glioblastoma Multiforme." Curr Pharm Des, 2015.

F-FDOPA PET and MRI characteristics correlate with degree of malignancy and predict survival in treatment-naïve gliomas: a cross-sectional study

C. Patel, E. Fazzari, A. Chakhoyan, J. Yao, C. Raymond, H. Nguyen, J. Manoukian, N. Nguyen, W. Pope, T. Cloughesy, P. Nghiemphu, J. Czernin, A. Lai, B. Ellingson, "F-FDOPA PET and MRI characteristics correlate with degree of malignancy and predict survival in treatment-naïve gliomas: a cross-sectional study." J Neurooncol, 2018.

Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI)

R. Harris, J. Yao, A. Chakhoyan, C. Raymond, K. Leu, L. Liau, P. Nghiemphu, A. Lai, N. Salamon, W. Pope, T. Cloughesy, B. Ellingson, "Simultaneous pH-sensitive and oxygen-sensitive MRI of human gliomas at 3 T using multi-echo amine proton chemical exchange saturation transfer spin-and-gradient echo echo-planar imaging (CEST-SAGE-EPI)." Magn Reson Med, 2018.

pH-weighted molecular MRI in human traumatic brain injury (TBI) using amine proton chemical exchange saturation transfer echoplanar imaging (CEST EPI)

B. Ellingson, J. Yao, C. Raymond, A. Chakhoyan, K. Khatibi, N. Salamon, J. Villablanca, I. Wanner, C. Real, A. Laiwalla, D. McArthur, M. Monti, D. Hovda, P. Vespa, "pH-weighted molecular MRI in human traumatic brain injury (TBI) using amine proton chemical exchange saturation transfer echoplanar imaging (CEST EPI)." Neuroimage Clin, 2019.

Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry

A. Chakhoyan, J. Yao, K. Leu, W. Pope, N. Salamon, W. Yong, A. Lai, P. Nghiemphu, R. Everson, R. Prins, L. Liau, D. Nathanson, T. Cloughesy, B. Ellingson, "Validation of vessel size imaging (VSI) in high-grade human gliomas using magnetic resonance imaging, image-guided biopsies, and quantitative immunohistochemistry." Sci Rep, 2019.

Probabilistic independent component analysis of dynamic susceptibility contrast perfusion MRI in metastatic brain tumors

A. Chakhoyan, C. Raymond, J. Chen, J. Goldman, J. Yao, T. Kaprealian, N. Pouratian, B. Ellingson, "Probabilistic independent component analysis of dynamic susceptibility contrast perfusion MRI in metastatic brain tumors." Cancer Imaging, 2019.

pH-weighted amine chemical exchange saturation transfer echoplanar imaging (CEST-EPI) as a potential early biomarker for bevacizumab failure in recurrent glioblastoma

J. Yao, C. Tan, J. Schlossman, A. Chakhoyan, C. Raymond, W. Pope, N. Salamon, A. Lai, M. Ji, P. Nghiemphu, L. Liau, T. Cloughesy, B. Ellingson, "pH-weighted amine chemical exchange saturation transfer echoplanar imaging (CEST-EPI) as a potential early biomarker for bevacizumab failure in recurrent glioblastoma." J Neurooncol, 2019.

Metabolic characterization of human IDH mutant and wild type gliomas using simultaneous pH- and oxygen-sensitive molecular MRI

J. Yao, A. Chakhoyan, D. Nathanson, W. Yong, N. Salamon, C. Raymond, S. Mareninov, A. Lai, P. Nghiemphu, R. Prins, W. Pope, R. Everson, L. Liau, T. Cloughesy, B. Ellingson, "Metabolic characterization of human IDH mutant and wild type gliomas using simultaneous pH- and oxygen-sensitive molecular MRI." Neuro Oncol, 2019.

F-FDOPA PET uptake and non-enhancing tumor volume predict malignant transformation and overall survival in low-grade gliomas

T. Oughourlian, J. Yao, J. Schlossman, C. Raymond, M. Ji, H. Tatekawa, N. Salamon, W. Pope, J. Czernin, P. Nghiemphu, A. Lai, T. Cloughesy, B. Ellingson, "F-FDOPA PET uptake and non-enhancing tumor volume predict malignant transformation and overall survival in low-grade gliomas." J Neurooncol, 2020.

Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study

J. Yao, A. Hagiwara, C. Raymond, S. Shabani, W. Pope, N. Salamon, A. Lai, M. Ji, P. Nghiemphu, L. Liau, T. Cloughesy, B. Ellingson, "Human IDH mutant 1p/19q co-deleted gliomas have low tumor acidity as evidenced by molecular MRI and PET: a retrospective study." Sci Rep, 2020.

Multiparametric MR-PET Imaging Predicts Pharmacokinetics and Clinical Response to GDC-0084 in Patients with Recurrent High-Grade Glioma

B. Ellingson, J. Yao, C. Raymond, D. Nathanson, A. Chakhoyan, J. Simpson, J. Garner, A. Olivero, L. Mueller, J. Rodon, E. Gerstner, T. Cloughesy, P. Wen, "Multiparametric MR-PET Imaging Predicts Pharmacokinetics and Clinical Response to GDC-0084 in Patients with Recurrent High-Grade Glioma." Clin Cancer Res, 2020.

Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma

K. Patel, J. Yao, C. Raymond, W. Yong, R. Everson, L. Liau, D. Nathanson, H. Kornblum, C. Wang, T. Oughourlian, A. Lai, P. Nghiemphu, W. Pope, T. Cloughesy, B. Ellingson, "Decorin expression is associated with predictive diffusion MR phenotypes of anti-VEGF efficacy in glioblastoma." Sci Rep, 2020.

Multiparametric MR-PET measurements in hypermetabolic regions reflect differences in molecular status and tumor grade in treatment-naïve diffuse gliomas

H. Tatekawa, A. Hagiwara, H. Uetani, J. Yao, T. Oughourlian, S. Bahri, C. Wang, C. Raymond, A. Lai, T. Cloughesy, P. Nghiemphu, L. Liau, W. Pope, N. Salamon, B. Ellingson, "Multiparametric MR-PET measurements in hypermetabolic regions reflect differences in molecular status and tumor grade in treatment-naïve diffuse gliomas." J Neurooncol, 2020.

Diffusion Magnetic Resonance Imaging Phenotypes Predict Overall Survival Benefit From Bevacizumab or Surgery in Recurrent Glioblastoma With Large Tumor Burden

K. Patel, R. Everson, J. Yao, C. Raymond, J. Goldman, J. Schlossman, J. Tsung, C. Tan, W. Pope, M. Ji, N. Nguyen, A. Lai, P. Nghiemphu, L. Liau, T. Cloughesy, B. Ellingson, "Diffusion Magnetic Resonance Imaging Phenotypes Predict Overall Survival Benefit From Bevacizumab or Surgery in Recurrent Glioblastoma With Large Tumor Burden." Neurosurgery, 2020.

Maximum Uptake and Hypermetabolic Volume of 18F-FDOPA PET Estimate Molecular Status and Overall Survival in Low-Grade Gliomas: A PET and MRI Study

H. Tatekawa, J. Yao, T. Oughourlian, A. Hagiwara, C. Wang, C. Raymond, A. Lai, T. Cloughesy, P. Nghiemphu, L. Liau, N. Salamon, B. Ellingson, "Maximum Uptake and Hypermetabolic Volume of 18F-FDOPA PET Estimate Molecular Status and Overall Survival in Low-Grade Gliomas: A PET and MRI Study." Clin Nucl Med, 2020.

"Aerobic glycolytic imaging" of human gliomas using combined pH-, oxygen-, and perfusion-weighted magnetic resonance imaging

A. Hagiwara, J. Yao, C. Raymond, N. Cho, R. Everson, K. Patel, D. Morrow, B. Desousa, S. Mareninov, S. Chun, D. Nathanson, W. Yong, G. Andrei, A. Divakaruni, N. Salamon, W. Pope, P. Nghiemphu, L. Liau, T. Cloughesy, B. Ellingson, ""Aerobic glycolytic imaging" of human gliomas using combined pH-, oxygen-, and perfusion-weighted magnetic resonance imaging." Neuroimage Clin, 2021.

Influence of phosphate concentration on amine, amide, and hydroxyl CEST contrast

J. Yao, C. Wang, B. Ellingson, "Influence of phosphate concentration on amine, amide, and hydroxyl CEST contrast." Magn Reson Med, 2021.

F-FDOPA PET, Relative Cerebral Blood Volume, and Apparent Diffusion Coefficient in Treatment-Naïve Diffuse Gliomas with Different Molecular Subtypes

H. Tatekawa, A. Hagiwara, J. Yao, T. Oughourlian, I. Ueda, H. Uetani, C. Raymond, A. Lai, T. Cloughesy, P. Nghiemphu, L. Liau, W. Pope, N. Salamon, B. Ellingson, "F-FDOPA PET, Relative Cerebral Blood Volume, and Apparent Diffusion Coefficient in Treatment-Naïve Diffuse Gliomas with Different Molecular Subtypes." J Nucl Med, 2021.

Detection of cerebral reorganization associated with degenerative cervical myelopathy using diffusion spectral imaging (DSI)

C. Wang, L. Holly, T. Oughourlian, J. Yao, C. Raymond, N. Salamon, B. Ellingson, "Detection of cerebral reorganization associated with degenerative cervical myelopathy using diffusion spectral imaging (DSI)." J Clin Neurosci, 2021.

Minimizing echo and repetition times in magnetic resonance imaging using a double half-echo k-space acquisition and low-rank reconstruction

M. Bydder, F. Ali, V. Ghodrati, P. Hu, J. Yao, B. Ellingson, "Minimizing echo and repetition times in magnetic resonance imaging using a double half-echo k-space acquisition and low-rank reconstruction." NMR Biomed, 2021.

F-FDOPA uptake for lower-grade gliomas

H. Tatekawa, H. Uetani, A. Hagiwara, J. Yao, T. Oughourlian, I. Ueda, C. Raymond, A. Lai, T. Cloughesy, P. Nghiemphu, L. Liau, S. Bahri, W. Pope, N. Salamon, B. Ellingson, "F-FDOPA uptake for lower-grade gliomas." J Neurooncol, 2021.

Relative oxygen extraction fraction (rOEF) MR imaging reveals higher hypoxia in human epidermal growth factor receptor (EGFR) amplified compared with non-amplified gliomas

T. Oughourlian, J. Yao, A. Hagiwara, D. Nathanson, C. Raymond, W. Pope, N. Salamon, A. Lai, M. Ji, P. Nghiemphu, L. Liau, T. Cloughesy, B. Ellingson, "Relative oxygen extraction fraction (rOEF) MR imaging reveals higher hypoxia in human epidermal growth factor receptor (EGFR) amplified compared with non-amplified gliomas." Neuroradiology, 2021.

Quantification of tumor microenvironment acidity in glioblastoma using principal component analysis of dynamic susceptibility contrast enhanced MR imaging

H. Akbari, A. Kazerooni, J. Ware, E. Mamourian, H. Anderson, S. Guiry, C. Sako, C. Raymond, J. Yao, S. Brem, D. O'Rourke, A. Desai, S. Bagley, B. Ellingson, C. Davatzikos, A. Nabavizadeh, "Quantification of tumor microenvironment acidity in glioblastoma using principal component analysis of dynamic susceptibility contrast enhanced MR imaging." Sci Rep, 2021.

A physical phantom for amine chemical exchange saturation transfer (CEST) MRI

J. Yao, C. Wang, C. Raymond, B. Bergstrom, X. Chen, K. Das, H. Dinh, Z. Kim, A. Le, M. Lim, J. Pham, J. Prusan, S. Rao, D. Nathanson, B. Ellingson, "A physical phantom for amine chemical exchange saturation transfer (CEST) MRI." MAGMA, 2021.

A study of 3D radial density adapted trajectories for sodium imaging

M. Bydder, F. Ali, A. Saucedo, A. Hagiwara, C. Wang, A. Pham, J. Yao, B. Ellingson, "A study of 3D radial density adapted trajectories for sodium imaging." Magn Reson Imaging, 2021.

Diffusion MRI is an early biomarker of overall survival benefit in IDH wild-type recurrent glioblastoma treated with immune checkpoint inhibitors

A. Hagiwara, T. Oughourlian, N. Cho, J. Schlossman, C. Wang, J. Yao, C. Raymond, R. Everson, K. Patel, S. Mareninov, F. Rodriguez, N. Salamon, W. Pope, P. Nghiemphu, L. Liau, R. Prins, T. Cloughesy, B. Ellingson, "Diffusion MRI is an early biomarker of overall survival benefit in IDH wild-type recurrent glioblastoma treated with immune checkpoint inhibitors." Neuro Oncol, 2021.

Paradoxical Association Between Relative Cerebral Blood Volume Dynamics Following Chemoradiation and Increased Progression-Free Survival in Newly Diagnosed IDH Wild-Type MGMT Promoter Methylated Glioblastoma With Measurable Disease

J. Goldman, A. Hagiwara, J. Yao, C. Raymond, C. Ong, R. Bakhti, E. Kwon, M. Farhat, C. Torres, L. Erickson, B. Curl, M. Lee, W. Pope, N. Salamon, P. Nghiemphu, M. Ji, B. Eldred, L. Liau, A. Lai, T. Cloughesy, C. Chung, B. Ellingson, "Paradoxical Association Between Relative Cerebral Blood Volume Dynamics Following Chemoradiation and Increased Progression-Free Survival in Newly Diagnosed IDH Wild-Type MGMT Promoter Methylated Glioblastoma With Measurable Disease." Front Oncol, 2022.

Visualization of tumor heterogeneity and prediction of isocitrate dehydrogenase mutation status for human gliomas using multiparametric physiologic and metabolic MRI

A. Hagiwara, H. Tatekawa, J. Yao, C. Raymond, R. Everson, K. Patel, S. Mareninov, W. Yong, N. Salamon, W. Pope, P. Nghiemphu, L. Liau, T. Cloughesy, B. Ellingson, "Visualization of tumor heterogeneity and prediction of isocitrate dehydrogenase mutation status for human gliomas using multiparametric physiologic and metabolic MRI." Sci Rep, 2022.

Teaching

Teaching experience 1

Teaching experience 2

Services

February 2022 - Present: UCSF Postdoctoral Scholar Association (PSA) Outreach Officer

Jingwen Yao

CV